Photocatalytic Transformations of the Resveratrol Derivative in Microflow Reactor

A simple and efficient protocol is utilized for the transformation studies of a thiophene analog E-resveratrol by photocatalytic oxygenation using an anionic cationic free-base porphyrin, as well their manganese(III) complexes. The starting substrate was chosen representative heterostilbenes with proven good antioxidant activity. experiments were carried out in two photoreactor types (batch microflow reactor) to investigate impact reactor type design on conversion photoproduct composition. NMR spectroscopy UHPLC/MS analyses applied identification quantification four photoproducts (Z-1, 2, 3, 4), results isomerization, dimerization, cyclization, oxygenation. Different yields obtained batch reactor. In performed reactor, Z-1 most dominant because it constantly removed from reaction mixture. Therefore, formation other products (2, 4, undefined) whose precursor avoided. This not case Additionally, all reactions tested significantly accelerated making preferred resveratrol derivative.